Signaling peptides play fundamental roles in cell-to-cell communication and intracellular pathways. 740 Y-P is being studied for its role in cellular signaling and potential research applications.
A phosphopeptide derived from IRS-1 protein that activates PI3K signaling. Studied in preclinical models for its role in insulin-like metabolic and proliferative pathways.
Also Known As
740Y-P
What is 740 Y-P?
740 Y-P is classified under the Signaling category of peptides. A phosphopeptide derived from IRS-1 protein that activates PI3K signaling. Studied in preclinical models for its role in insulin-like metabolic and proliferative pathways.
Mechanism of Action: PI3K activator that binds to the p85 regulatory subunit, mimicking receptor tyrosine kinase signaling to activate the PI3K/Akt pathway.
Cell Signaling Research
Primary Research Areas: Cell survival signaling, insulin sensitivity research, PI3K pathway studies, metabolic regulation.
Key Research Findings: Has been used extensively in cell biology research to activate PI3K signaling. Studies show it can promote cell survival and proliferation through Akt phosphorylation.
Safety Profile & Considerations
Research compound with limited in vivo safety data. PI3K activation must be carefully controlled as excessive signaling can promote abnormal cell growth.
Related Research Topics
Understanding 740 Y-P requires familiarity with these related concepts in signaling research. Each topic represents a broader field that intersects with current peptide research.
References & Further Reading
Derossi D, et al. Cell internalization of the third helix of Antennapedia homeodomain. J Biol Chem. 1996;271(30):18188-93.
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